الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 86 |  |  |
| | | from | 86 | | |
Abstract
Myopia is a major growing public health problem worldwide. It is one of the most prevalent disorders of the eye. The mean prevalence of high myopia increased over time in Egypt, where it increased from 0.2% in 1960 to 7.4% in 1976 and 10.8% in 2015.
Optical coherence tomography (OCT) is a noninvasive, painless, quick and precise technology that can be used for interpreting tissue structure and function that uses near-infrared light.
Heidelberg Spectralis provides Glaucoma Module Premium Edition (GMPE) with a new, objective method of ONH analysis using BMO. The termination of Bruch’s membrane at the ONH marks the opening through which RGC axons exit the eye to form the choroidal and scleral portions of the neural canal; this anatomic opening is termed Bruch’s membrane opening (BMO). The minimum distance from the BMO to the internal limiting membrane is termed Bruch’s Membrane Opening - Minimum Rim Width (BMO-MRW).
The aim of this study was to evaluate the macula and nerve fiber layer in myopic eyes using the optical coherence tomography.
The study included 90 myopic eyes that were selected randomly from 90 patients attending the Alexandria University Hospital Ophthalmology Clinic in 2020. They were classified into 3 groups; mild, moderate and high myopia.
The study included 49 males (54.4%) and 41 females (45.6%) with age range between 19 – 40 years. with no statistically significant differences between the three groups according to the demographic data.
There was a statistically significant increase in the central macular thickness, inner inferior, inner nasal and inner temporal sectors in the high myopia group compared to the moderate and mild myopia groups. There were more macular pathologies in the high myopia group compared to the moderate and mild myopia groups.
In the mild myopia group, there was a statistically significant positive correlation between the SE and macular inner superior sector. In the moderate group, there was a significant positive correlation between the axial length and the CMT and the thickness of the inner nasal and outer temporal sectors. Also, there was a significant negative correlation between the SE and CMT. In the high myopia group, there was a significant negative correlation between the axial length and macular thickness in all sectors except the CMT which showed a significant positive correlation. On the other hand, there was a significant positive correlation between the SE and macular thickness in all sectors except the CMT which showed a significant negative correlation.
The RNFLT was thinner in the high myopia group compared to the moderate and mild myopia groups in the nasal, nasal inferior and temporal superior sectors.
In the mild myopia group, there was no statistically significant correlation between the AL and the SE and the RNFLT. In the moderate group, there was a significant negative correlation between RNFLT in the nasal and nasal superior sectors and the axial length. Also, there was a significant negative correlation between the RNFLT in the nasal sector and the SE. In the high myopic group, there was a significant negative correlation between the RNFLT in the nasal and nasal inferior sectors and the axial length. Also, there was a significant positive correlation between the RNFLT in the nasal, nasal inferior and nasal superior sectors and the SE.
The circumpapillary RNFLT in all myopia groups was significantly thinner in the 4.1 mm circle compared to the 3.5 mm circle. Similarly the circumpapillary RNFL was significantly thinner in the 4.7 mm circle compared to the 4.1 mm circle in all myopia groups.
In the mild and moderate myopia groups, there was no statistically significant difference in the RNFLT between the non-tilted and tilted discs using the 3.5 mm, 4.1 mm and 4.7 mm circles. In the high myopia group, using the circumpapillary RNFLT circle 3.5 mm, the tilted discs with PPA group was statistically significantly thinner in the nasal superior and temporal inferior sectors compared to the non-tilted discs with no PPA and tilted discs with no PPA groups. Using the circumpapillary RNFLT circle 4.1 mm, the tilted discs with PPA group was statistically significantly thinner in the temporal inferior sector compared to the non-tilted discs with no PPA and tilted discs with no PPA groups. There was no statistically significant difference in the thickness between the three groups using the circumpapillary RNFLT 4.7 mm circle.
BMO-MRW map showed non-significant lower FP and higher SP compared to RNFLT map in both mild and moderate myopic groups. On the other hand, the RNFLT map showed non-significant lower FP and higher SP compared to BMO-MRW map in the high myopic group.