الفهرس 
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Abstract
202 rectal swabs were collected from Dogs and Cats suffering from hemorrhagic enteritis manifested by bloody diarrhea from Damietta and El-Dakahlia Governorates in order to make studies on multidrug resistant bacteria causing hemorrhagic enteritis. Total bacterial isolates were 104. Out of the 104 bacterial isolates, E. coli was the most prevalent isolate (44.23%), followed by Proteus vulgaris (11.53%), Proteus mirabilis (9.62%), Klebsiella species (8.65%), C. perfringens (4.81%), Pseudomonas aeruginosa (3.85%), Enterobacter species (3.85%), Salmonella species (2.88%), Shigella species (2.88%), and Providencia rettgeri (1.92%). The antimicrobial resistance of E. coli isolated were reported to Amoxicillin/Clavulanic acid, Cephalexin, Ceftriaxone, Trimethoprim/sulphamethoxazole, Tetracycline and Erythromycin. Multiplex Polymerase Chain Reaction demonstrated that 4 serotypes were positive for (stx1), 3 serotypes were positive for (stx2), while all isolates were negative for (eaeA) virulence genes. Some resistant genes of E. coli were detected by Multiplex Polymerase Chain Reaction, where all E. coli isolates were negative for blaOXA gene. Only E. coli isolate O91:H21 was positive for blaCTX-M1 gene, representing 20% of the tested isolates. The blaTEMgene was detected in three E. coli isolates O55:H7, O91:H21 and O128:H2, by a percentage of 60%.