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العنوان
Comparative study between coplanar Versus non-coplanar intensitymodulated
Radiation therapy (imrt)Techniques in treatment of brain tumor /
المؤلف
Al Dulaimi, Zeyad Tareq Radeef.
هيئة الاعداد
باحث / زياد طارق رديف الدليمى
مشرف / عنايات ابراهيم فهمى
مشرف / سناء على البنهاوى
مشرف / دعاء محمود الزيات
مناقش / طه اسماعيل محمود حواله
مناقش / شريف فاروق الزواوى
الموضوع
Radiation Science. Radiobiology.
تاريخ النشر
2021.
عدد الصفحات
76 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
17/2/2021
مكان الإجازة
جامعة الاسكندريه - معهد البحوث الطبية - علوم الاشعاع
الفهرس
Only 14 pages are availabe for public view

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from 76

Abstract

The aim of radiation therapy is to give the subject a therapeutic dose of radiation
while limiting the side effects induced by the application of the dose to the tissues and vital
organs around it. The continuing search to reach an optimum dose delivery has led the field
of radiation therapy to create innovative methods that integrate scientific advancements.
New methods include three-dimensional conformal radiation therapy (3D-CRT), intensitymodulated
radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) are
widely used in radiation therapy today in the treatment of cancers. In the IMRT and
VMAT techniques and 3D conformal techniques, clinical and dosimetric findings of IMRT
in brain tumors were compared between coplanar and non-coplanar. Superior dose
conformity and homogeneity were shown by IMRT. Furthermore, IMRT reduced normal
tissue doses, notably in cases where vital structures such as the optic nerves and the brain
stem were affected by the target.
The focus of this work was dosimetric assessment research on the effects of using a
non-coplanar procedure relative to the coplanar IMRT treatment plans for brain tumor
patients.
This study included 15 patients with brain cancer. For each patient, two treatment
plans (coplanar and non-coplanar IMRT) using energies (6MV) is done and Dose-volumehistogram
was analyzed (DVH).
Our results showed that:
 The mean dose received by PTV D5%, D95%, D98%, and D106% were insignificantly
different between the two techniques. Regarding organ at risk, dose comparison for
two techniques showed insignificant difference.
 There were also no major discrepancies in homogeneity index (HI) and
conformation number (CN) between the two techniques.
 The plan quality and treatment efficiency parameters comparison showed: no
statistically significant differences in the coplanar and non-coplanar IMRT plans in
terms of PTV coverage and OARs.