الفهرس 
Aim of the workOnly 14 pages are availabe for public view
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Abstract
Nonalcoholic fatty liver disease (NAFLD), ranges from non alcoholic simple steatosis (SS) to non alcoholic steatohepatitis (NASH), NASH–related cirrhosis and hepatocellular carcinoma (216).
Liver histology remains the gold standard for assessing disease severity in NAFLD. Being invasive, biopsy is unsuitable for community studies and particulary for studying hepatic fibrosis progression and also histological assessment of NAFLD due to sampling error (217).
Using Fibroscan is effectively and noninvasively discriminate between simple fatty liver and NASH in obese. Data regarding this profile of fibrosis in the population has also been unknown (218).
Resistin, a cytokine originating from adipose tissue, is involved in insulin resistance and also initiates proinflammatory signaling from hepatic stellate cells. Resistin is an adipocyte- derived signaling polypeptide was originally identified in 2001 (219).
The aim of the present study was to study the correlation between fibroscan and resistin level in Non Alcoholic fatty liver patients.
The study was conducted in Shebin El-Kom Fever Hospital, including 90 participants. The studied patients were recruited from hepatology department during the period from July 2019 to January 2020.
In this study 60 subjects enrolled with NAFLD and 30 Non obese apparently healthy people. Diagnosis based on chronic elevation of transaminases (> 1.5 times the upper normal value for 3 months in absence of chronic liver disease) and bright liver by U/S.
Participants were classified into three groups:
group I: include 27 patients with NASH.
group II: include 33 patients with simple steatosis.
group III: include 30 healthy subjects as control.
All patients were subjected to the following:
1- Personal history.
2- Present history of complaint.
3- Clinical examination.
4- Laboratory tests (CBC, liver function tests, etc.)
5- Abdominal ultrasound.
6- Fibroscan.
7- Specific investigations:
All included patients and control group were subjected to determination of serum resistin level (by ELISA technique).