Search In this Thesis
   Search In this Thesis  
العنوان
Modulatory physiological, histopathlogical and immunological effects of honey and bee venom on the hepatotoxcicty induced by lipopolysaccharides and carbon tetrachloride /
المؤلف
Kasem, Suzan Alaa Ismail.
هيئة الاعداد
باحث / سوزان علاء إسماعيل قاسم
مشرف / ناجي صادق توفيق
مشرف / نهي محمد عبدالرحيم
الموضوع
Bees - Therapeutic use. Bees - Venom - Therapeutic use.
تاريخ النشر
2021.
عدد الصفحات
156 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الحيوان والطب البيطري
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنيا - كلية العلوم - علم الحيوان
الفهرس
Only 14 pages are availabe for public view

from 176

from 176

Abstract

Hepatotoxicity implies chemical-driven liver damage. Certain medicinal agents, when taken in overdoses and sometimes even when introduced within therapeutic ranges, may injure the organ. Chemicals that cause liver injury are called hepatotoxins. In the present study, the protective effects of Honey and Bee venom either independently or in combination against hepatoxicity in male albino rats were investigated. The administration of honey and/or BV showed a significant hepatoprotective potential effect against LPS+CCl4 induced hepatoxicity in rats. The statistical analysis obtained in the current study showed positive percentages of improvement in liver function enzymes to some extent.The administration of honey and BV to the LPS/CCl4 group resulted in the enhancement in the oxidative stress biomarker, LPx, suggesting their antioxidant role. The administration of honey and BV individually or together showed the highest percentages of improvement in the hematological, kidney parameters and histopathological changes in the liver as a result of LPS/CCl4 exposure.