الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Wild Felidae are strict carnivores and play an important role in the ecological balance. As it occupies higher trophic level, it regulates the size of prey population and have indirect effect on plant propagation and distribution. Felidae are susceptible to bacterial affections such as members of enterobacteriaceae & Helicobacter spp. Wild Felidae in zoo and breeding center may be considered as a source of diseases not only for other animals but also for human such as veterinarians, workers, and visitors. Such close contact between wild animals and humans creates opportunities for spreading of zoonotic diseases. The study was performed on 30 animals belong to family Felidae, including (16 lions, 2 tigers, and 2 cheetah) in Giza Zoo and (5 lions and 5 wild cats) in private zoo. All animals were apparent healthy and showing no signs of diseases except eight lions have history of vomition. 75 fecal samples were collected, 65 from Giza Zoo and 10 from private zoo. Samples were subjected to standard bacteriological techniques for bacterial isolation and biochemical, serological, and molecular identification. Four members of family Enterobacteriaceae including E. coli, Salmonella, Shigella and proteus were isolated. E. coli and Salmonella isolates were subjected to serological and molecular identification and antimicrobial sensitivity test. Three serovars of E. coli (O126: K71, O78: K80 and O111: K58) and 2 serovars of Salmonella (S. Southampton and S. Bovismorbificans) were recorded. E. coli isolates showed high resistance to Cefaclor (100%), Amoxicillin-Clavulanic acid (40%), Cefoxitin (100%), Tobramycin (100%), Cefadroxil (100%). Salmonella isolates showed high resistance to
Cefaclor (100%), Cefoxitin (100%), Tobramycin (66.7%), Cefadroxil (100%). The detection of antibiotic resistant genes confirmed the presence of blaTEM and blaSHV in all isolates of E. coli and Salmonella that showing resistant to Cefaclor, Cefoxitin, and Amoxicillin-Clavulanic acid, and the presence of the aadA2 in some isolates of E. Coli and all Isolates of Salmonella showing resistant to tobramycin.