الفهرس 
Epidemiology of InfectionOnly 14 pages are availabe for public view
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Abstract
The Aim of this study is to assess the value of using the culture-guided Antibiotic sensitivity versus standard triple therapy in successful H. pylori eradication
43 of group A patient (86%) showed successful h. pylori eradication after culture guided antibiotic therapy.
0nly 20 of group B patients (60%) showed successful h. pylori eradication after standard triple therapy.
The study showed high resistant rates of h. pylori to clarithromycin and amoxicillin and metronidazole and gradually increasing resistance against levofloxacin.
Countries like Egypt seem to have a high clarithromycin resistance, and a large-scale clinical trial is needed to choose the first-line therapy for eradication of H. pylori infection.
Unfortunately, many patients infected with H. pylori in whom treatment has failed, have concurrent dual resistance to clarithromycin and metronidazole, or even triple resistance to clarithromycin, metronidazole, and fluoroquinolone (using culture-based antimicrobial susceptibility testing).
Given the alarmingly high antibiotic resistance in H. pylori, gastroenterologists should change the empiric H. pylori treatment to an antimicrobial susceptibility testing-guided precision treatment.
Culture guided therapy is expensive and laborious but as the results showed, it is definitely the best method to achieve complete h. pylori eradication from the first time.