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العنوان
The Role of Surfactants in Inhibition of Uropathogenic Escherichia Coli Biofilm in Catheterized Patients /
المؤلف
Ahmed, Omnia Asharf.
هيئة الاعداد
باحث / امنية اشرف احمد محيى الدين
مشرف / اسماعيـــل صديــــق محمــــد
مناقش / محمد فؤاد الصاوى
مناقش / احسان عبد الصبور
الموضوع
Microbiology.
تاريخ النشر
2021
عدد الصفحات
121 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
صيدلة
الناشر
تاريخ الإجازة
29/11/2021
مكان الإجازة
جامعة أسيوط - كلية الصيدلة - Microbiology and Immunology
الفهرس
Only 14 pages are availabe for public view

from 134

from 134

Abstract

UropathogenicE. coli (UPEC) is a bacterium that colonizes the bladder. UPEC favors long-term investments bacterial hydrophobic interactions also play a role in bacterial adherence to the surface and facilitate biofilm formation which is common among catheterization patients. UPEC were 13% among the isolates obtained from urine samples.
In present study we evaluated curli encoding gene (CsgA) that responsible for biofilm formation by PCR, all E.coli isolates were biofilm producer (13%). Three different surfactants (Tween 80, SDS and CTMA) as potential solution for this problem by microtitre plate inhibition assay and we evaluated the antimicrobial activity of different surfactants by cup diffusion method.