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العنوان
Biochemical and Molecular Study of miR-15b and 378a in neonatal sepsis /
المؤلف
Ellaban, Rania Elsayed Elsayed Abd-Elfattah
هيئة الاعداد
باحث / رانيا السيد السيد عبد الفتاح اللبان
مشرف / صلاح محمد القوصي
مشرف / ايمان صلاح الدين السيد عرفات
مشرف / ايمان عبدالله محمود فوده
الموضوع
MiRNA 15b and MiRNA 378a Neonatal Sepsis
تاريخ النشر
2021
عدد الصفحات
140 P.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
25/10/2021
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Infected neonates with sepsis are a clinical case that need to
quickly diagnosing as well as management. Biomarkers have a
decisive role in disorder physiological process associated with sepsis,
they can illustrate the extent risk of septicemia and can discriminate
the source infection; if it is from bacteria, fungi or virus as well as
from local or systemic sepsis.
MicroRNAs (miRNA) are single-stranded non-coding RNAs.A
lot of these microRNAs completely or partially were implicated in
gene silencing; they’re additionally concerned in the transcriptional
activation and co-activation of many genes. Furthermore, the
misregulation of several miRNAs is linked to the development of
certain diseases in humans and other organisms.
As result to the scarcity of published researches which
demonstrate the role of miRNAs in diagnosis of neonatal sepsis. So,
we conducted this research to evaluate the role of miRNA 15b and
miRNA 378a as diagnostic biomarkers for neonatal sepsis.