الفهرس | Only 14 pages are availabe for public view |
Abstract Residues of veterinary drugs in poultry meat have bad health effects on humans (e.g., increase antibacterial resistance, hypersensitivity, carcinogenicity and mutagenicity) which make the control of veterinary drug uses and residues an important goal to insure consumer protection. This study was performed to determine erythromycin residues, tilmicosin residues and the effect of l.carnitine on erythromycin and tilmicosin residues in different tissues of chickens (liver, kidney and breast muscle) and plasma following multiple oral doses of the drugs using microbiological assay. The experiment was conducted on 48 chickens, they were randomly allocated into four equal groups; 1-group A (n=12) was orally administrated 4 gm /litter drinking water erythromycin for 5 consecutive days. Samples ( liver, kidney and breast muscle and plasma) were collected daily from each slaughtered bird at 1 st , 2 nd and 3 rd day after 24 h following the last oral dose, 2-group B (n=12) was orally administrated 4 gm /litter drinking water erythromycin for 5 consecutive days and 162.5 mg /2 litter drinking water l.carnitine for 2 consecutive days. Samples (liver, kidney and breast muscle and plasma) were collected daily from each slaughtered bird at 1 st , 2 nd and 3 rd day after 24 h following the last oral dose, 3- group C (n=12) was orally administrated 1 ml /litter drinking water tilmicosin for 5 consecutive days. Samples (liver, kidney and breast muscle and plasma) were collected daily from each slaughtered bird at 1 st , 2 nd and 3 rd day after 24 h following the last oral dose, 2- group D (n=12) was orally administrated 1 ml /litter drinking water tilmicosin for 5 consecutive days and 162.5 mg /2 litter drinking water l.carnitine for 2 consecutive days. Samples (liv. |