الفهرس 
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Abstract
The aim of this study was to assess the predictors of the thoracoscopic interventions and their effect on the outcome of pleurodesis during management of malignant pleural effusion. The primary objective was to assess the hypothesis that tumor burden is associated with higher pleurodesis failure. The secondary objective was to assess if tumor type, performance status can affect pleurodesis outcome, as well as determination of thoracoscopic complications, the length of hospital stay and the survival time. This study was conducted at Chest Medicine Department, Mansoura University, Egypt and Oxford Pleural Unit, UK during the period from August 2018 to June 2021. Ethical approval had been obtained from Institutional Research Board (IRB) of Faculty of Medicine, Mansoura University (code no: MD.19.07.202). The study protocol was reviewed and discussed with clinical trials and research governance at the University of Oxford and the need for consent was waived as this was a retrospective review. This was a retrospective cohort study of 102 patients 53 males and 49 females who underwent thoracoscopy, had malignant pleural effusion confirmed by histopathology, and followed by talc pleurodesis at the Oxford Pleural Unit from March 2011 to December 2018. The enrolled patients were further divided according to the outcome of pleurodesis: successful group included 68 patients while the failed group included 34 patients. Successful group included 21 patients with mesothelioma and 47 patients with non-mesothelioma. Failed group included 15 patients with mesothelioma and 19 patients with non-mesothelioma.