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العنوان
Atherosclerotic burden of coronary arteries in diabetic patients using multi-slice computed tomography angiography /
المؤلف
El-said , Karim Mohamed Zaki .
هيئة الاعداد
باحث / كريم محمد زكي السيد
مشرف / هالة محفوظ بدران
مشرف / غادة محمود سلطان
مناقش / هالة محفوظ بدران
الموضوع
Angiography. Atherosclerotic plaque Imaging. Computed Tomography Angiography. Coronary Artery Disease diagnostic imaging.
تاريخ النشر
2021.
عدد الصفحات
65 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
28/9/2021
مكان الإجازة
جامعة المنوفية - كلية الطب - القلب والاوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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from 77

Abstract

By the year 2025, there will be more than 300 million type 2 diabetes sufferer worldwide. This epidemic will be followed by a wave of cardiovascular disease. As because, diabetes is in fact a serious vascular disease with poor prognosis.
Coronary CTA is an emerging noninvasive technique for the evaluation of coronary stenosis and for the characterization of the atherosclerotic plaques.
This study was carried out at Police Hospitals aiming to evaluate the difference of the atherosclerotic burden of coronary arteries between patients suffering from diabetes mellitus and non-diabetic patients by utilization of coronary CTA. We included a total of 100 cases with coronary atherosclerosis who were divided into two groups; the non-diabetic group included 63 cases who had not had diabetes mellitus, and the diabetic group which included the remaining 37 cases who had diabetes.
All of the included cases were subjected to complete history taking, thorough physical examination, and routine preoperative investigations. Additionally, echocardiography and coronary CTA were done for all cases.
Our results showed that:
 The diabetic group displayed significant younger age. However, gender and body mass index did not significantly differ between the two groups. Although smoking prevalence was comparable in the study groups, both hypertension and dyslipidemia had significantly higher prevalence in the diabetic group. Most of the studies echocardiographic variables were comparable between the two groups.
 HbA1c was increased significantly in the diabetic group compared to the non-diabetic group.
 There was an increased prevalence, extent, and severity of CAD for DM individuals .
 Obstructive lesions were significantly more common in the diabetic group.
 The total number of plaques was significantly higher in the diabetic group.
 There was a significant difference between the two groups regarding plaque type.
 Ca score was significantly elevated in the diabetic group compared to non-diabetics.