الفهرس 
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Abstract
Oral Squamous cell carcinoma (OSCC) is the eleventh most common cancer globally. Tumor stroma consists of various inflammatory cells resulting from the host-response to tumor cell. Increased tissue eosinophil levels have been reported in various malignancies including OSCC. Tissue eosinophilia is a regular finding in allergic and parasitic disorders, but their role still needs to be evaluated in OSCCs. Special stains like Congo red is a valuable diagnostic tool for detection of eosinophils because of their unique property to bind with eosinophils.
The Study objectives was to assess and compare eosinophilic infiltration in both metastatic and non-metastatic oral squamous cell carcinoma using Congo red stain and their correlation to the tumor grade.
Fifty histopathologically proven OSCC were included in this study and divided into two groups where the first group include 25 cases of metastatic OSCC and the remaining 25 cases are non-metastatic OSCC. Congo red was used as a special stain for eosinophils. Each specimen slide was viewed under high power in 10 consecutive microscopic fields for counting of eosinophils.
Histologic observations were documented, and results was tabulated and statistically analyzed.