الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 92 |  |  |
| | | from | 92 | | |
Abstract
The thermal therapy is one of the most important applications of the biomedical engineering over the centuries used in cure of many diseases such as asthma, arthritis, and infectious diseases such as syphilis and gonorrhea. The term of ”hyperthermia” has been received a lot of interest over the last decades in oncology research. It is a therapeutic technique that applies thermal energy to damage cancerous cells by means of electromagnetic waves. The effectiveness of hyperthermia in cancer therapy has been development based on fact that cancerous cells are more sensitive to temperature than normal cells. Moreover, several clinical studies have shown increase of toxicity of cancerous cells and make them more responsive to chemotherapy and radiotherapy to enhance treatment outcomes. The hyperthermia is considered a non- invasive treatment that does not require puncture the skin or any other body part using any medical instruments. However, it is based on coupling of electromagnetic waves into body using external device such as antenna, which are positioned in vicinity of a targeted area in the human body to elevate its temperature. The main objective of this thesis is to investigate the potential of using an inset‐fed rectangular slot microstrip antenna array (MSA) applicator operating at 2.45 GHz for breast cancer hyperthermia treatment. Hyperthermia using microwave radiation is considered as an effective method for treatment of breast cancer. The challenge in hyperthermia is to damage and kill the cancerous tissue by raising its temperature above 42°C without exposing healthy tissue to excessive temperature elevations. The thermal energy is coupled onto a breast tissue through eight slotted MSAs array applicator that transmits microwave energy. Modeling and simulations for the hyperthermia technique is performed using Computer Simulation Technology (CST) Studio 2019 software and are divided into three main tasks: • Generation of female breast model • Determination of distribution of power deposited in a breast tissue. • Determination of temperature distribution in the breast tissue. The results obtained shows that this MSA design is very suitable for clinical antenna array as hyperthermia breast cancer applicator. Besides that, the proposed system is capable for steering the array beam to different locations within breast by changing phase and feeding current distribution of antenna array elements to achieve a precise hyperthermia to cancerous tissues and minimal injury to normal tissues.