الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 142 |  |  |
| | | from | 142 | | |
Abstract
Zika Virus (ZIKV), is an emerging mosquito-borne virus, belongs to the flavivirus family. It is transmitted by various species of Aedes mosquitoes (Boorman JP et al., 1956) (Moore DL et al., 1975), the mosquito which is also found in Egypt.
The classic clinical picture of ZIKV infection resembles that of dengue fever and chikungunya, and is manifested by fever, conjunctivitis, headache, arthralgia, myalgia, and maculopapular rash (Simpson DI., 1964), a complex of symptoms that require differential diagnosis.
Although the disease is self-limiting, known previously to cause no fatality or permanent deformity, cases of neurologic manifestations and the Guillain–Barré syndrome - a form of temporary paralysis- were reported in adults (Beckham JD et al, 2016), in French Polynesia and in Brazil during ZIKV epidemics.
In obstetrics, ZIKV infection has been linked to unusually small heads (microcephaly) (eCDC, 2016) (Tetro JA., 2016) (Oliveira Melo AS et al., 2016) and brain damage in newborns. Other congenital defects such as blindness, deafness, and seizures have also been reported in children born to infected mothers (WHO, 2016).
The aim of this study is to contribute to the prevention of congenital infection in Egypt, its objective is to study silent ZIKV infection, or immunization in pregnant women, and to study the effect of immunization or past infection in