الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 104 |  |  |
| | | from | 104 | | |
Abstract
Hepatocellular carcinoma (HCC) accounts for 85 to 90% of primary liver
cancer cases. chronic hepatitis and cirrhosis formed the major preneoplastic
conditions in the majority of HCC.
The aim of this study was to distinguish the role of ADAM8 in improving
hepatocellular carcinoma (HCC) diagnosis when combined with alpha feto protein
(AFP).
This study was conducted on 70 subjects (41 male, 29 female) recruited from
the chronic liver diseases unit (outpatients and inpatients clinics), National Liver
Institute Hospital, Menoufia University, Egypt
The subjects involved in this study were classified into 3 groups , group one
included 20 healthy volunteers with normal laboratory investigations, , and no
history of liver disease; they were 10 (50%) males and 10 (50%) females with age
mean value of 35.3±14.2years, While group two included 19 patients with liver
cirrhosis. They were 13 (68.4%) males and 6(31.6%) females, with age mean value
of 44.6±13.6years, and group 3 included 31 patients with HCC. They were 18 (58.1
%) males and 13(41.9%) females, with age mean value of 55.8±9.5years.
All groups were subjected to thorough history taking, clinical examination,
abdominal ultrasonography and CT scanning.