الفهرس 
Introduction and RationalOnly 14 pages are availabe for public view
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Abstract
The aim of the present study is to assess the expression of IL-17 in SNP and in serum and to evaluate the role of IL-17 in the development of SNP in order to choose the optimum treatment for this condition. The study was conducted at the Otorhinolaryngology department and Allergy and Immunology department. Suez Canal University Hospital, Ismailia, Egypt.
The study was carried out from May 2016 to December 2017. Patients presenting with SNP and attending Suez Canal University Hospital in Otorhinolaryngology clinic, Allergy and Immunology clinic were recruited into the study. Those patients suffering from SNP and seeking medical advice were randomly divided into one of the three groups according to the skin prick test: group A: patients with SNP and were atopic (positive skin prick test).group B: patients with SNP and weren’t atopic (negative skin prick test). group C (control group): normal healthy persons used as a control for both groups A and B. They were matched age and gender of the study groups.
Written informed consent was obtained from all participants before performing any interventions, which were approved by the clinical research ethics committee of Faculty of Medicine, Suez Canal University.
Blood samples were taken from patients with nasal polyps for measurement of IL17A level by Enzyme-Linked Immunosorbent Assay (ELISA). Polyps were taken from all of the patients as samples. The polyps were fixed in 10% neutral-buffered formalin for a day. Paraffin embedded sections from nasal polyps were