الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
In this study we evaluated the clinical and radiographic effect of melatonin and hyaluronic acid on the new bone formation in maxillary sinus augmentation where this mixture was used as the sole grafting material in this technique and we compared it to the graftless technique.
In this study 16 patients were selected and divided into two groups. group I received melatonin and hyaluronic acid after sinus membrane elevation with simultaneous implant placement. And group II did not receive any materials after the procedure. Patients were evaluated clinically for pain, swelling, complications, and implant stability. And radiographically to measure the vertical bone height gain, bone density, and marginal bone level.
Before surgery, all patients were examined clinically and CBCT was taken for proper selection with the indicated criteria.
Also, scaling and root planning were done for optimal periodontal health. In addition, participants were instructed to rinse with 0.125% Chlorhexidine HCL antiseptic mouth-wash for 30 seconds prior to surgery.
The surgery was performed under local anesthesia. A trap-door lateral window technique was created using the piezoelectric device. Then sinus membrane was elevated and the implants were placed simultaneously after which implant stability was recorded. In group I, melatonin and hyaluronic acid were placed, whereas in group II no materials were placed. Finally flap was sutured after covering the window opening with a resorbable collagen membrane.
Patients were recalled along the first 7 days postoperatively to evaluate pain intensity, swelling, and complications, clinically. Then after 1 month and 6 months to measure vertical bone height gain, bone density, and marginal bone level, radiographically. Also, implant stability was recorded again after 6 months.
After preforming the statistical analysis it was found that bone density increased significantly in each group and also when compared group I to group II. Regarding pain, swelling, implant stability, vertical bone height gain, and marginal bone level, there was a significant difference in each group but the difference was insignificant between both groups.