الفهرس 
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Abstract
Cardiovascular disease is still the leading cause of mortality in the world. Several biomarkers have been investigated for the diagnosis and risk stratification of acute coronary syndrome (ACS): cardiac troponin, creatine kinase-myocardial band and high sensitive C-reactive protein (hs-CRP). Many biomarkers were associated with the development and progression of coronary heart disease. In the past, the role of hs-CRP in cardiovascular disease was controversial as a risk marker. It has been reported that elevated hs-CRP levels were associated with increased risk of adverse cardiovascular outcomes in patients with different CAD phenotypes. The aim of our study was to assess prognostic value of high sensitive C-reactive protein in patients with acute coronary syndrome. This was an observational study that was carried out on 50 patients at the department of cardiology, Tanta university hospitals throughout 6 months from February 2020. Statistical analysis revealed the following: 1- Among 50 patients, 26 of them are males with a percentage of 52.0%, group A have 7 cases (50%), group B have 19 cases (52.8%) and the other 24 are females with a percentage of 48.0%, group A have 7 cases (50%), group B have 17 cases (47.2 %) with the range of age in group A 39-55 and group B 29-56. 2- There were 19 Cases with unstable angina with a percentage of 38.0%, group A had 5 cases (35.7%), group B had 14 cases (38.9%), 11 Cases are NSTEMI with a percentage of 22.0% group A had two cases (14.3 %), group B had 9 cases (25 %), and the other 20 are STEMI with a percentage of 40.0% group A had 6 cases (42.8 %), group B had 14 cases (38.9%). 3- There was statistically significant positive correlation between High sensitive CRP (mg\l) and Total cholesterol, (mg/dL), LDL-C, (mg/dL), HDL-C, (mg/dL), Triglyceride, (mg/dL), stent implantation and Gensini score. 4- There was no statistically significant difference found between high sensitive CRP (mg\l) and sex, smoking, BMI and HTN and diabetes. 5- No statistically significant difference was found between high sensitive CRP and patterns of acute coronary syndrome and hospital complications. Finally, it is concluded that the measurement of CRP in patients with suspected coronary artery disease may be helpful in identifying a group of patients who may be at high risk of cardiac complications and these patients need aggressive cardiac management and close monitoring after discharge. Limitations of the study: It small sized study and done in one center, a large study on a large number of population in multiple centers is needed to validate the results.