الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
In the earliest times, nature environment played a main role as the chief source of medicinal extracts used, in addition to the source of several natural products that led to the progress of various drugs presently used for the cure of a wide spectrum of diseases Natural products extracts, have designed the root of the traditional medicine schemes However, it was only in the recent days that research focused on the identification then characterization of new compounds responsible for the medicinal properties (Newman Cragg, 2012). The crucial requirement of novel therapeutic alternatives, mainly for the dealing with various diseases led to the replacement of attention in rediscovering of natural products focusing in alternative sources such as the aquatic systems. It is perfect that nature will remain to be the main source of new structural leads. The oceans are considered the largest biome on earth, covering more than 70% of the Earth’s surface and host huge species diversity, with a much higher diversity of new marine organisms that still represent a largely unexplored reservoir of natural products, a vast potential source of diverse and new drugs with bioactive compounds and healthy food caused by the existence of secondary metabolites covering a wide-ranging field of structural classes and various biosynthetic origins (Carlos Jiménez, 2018).