الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
RV adaptation to diseases is complex and depends on many factors, the most important factor are the type and severity of myocardial injury stress, the time course of the disease (acute or chronic), and the time of onset of disease. Due to the complex geometry of RV it is difficult to find a simple, single reliable measure for RV systolic function assessment. 2D Speckle tracking echocardiography is an angle independent technique that allow assessment of segmental myocardial deformation. We aimed to Compare RV systolic function indices TAPSE, FAC, S’WAVE velocity, MPI as well as strain and strain rate before ASD Closure and 6 month after ASD closure. We included 2 groups in our study (group A) for patients underwent surgical closure and (group B) for patients underwent transcatheter device closure All participants in this study were subjected to full history taking, clinical examination, 12 lead ECG, 2D echocardiography using M mode and Doppler examination as well as 2Dspeckle tracking analysis of strain and strain rate. Our results had demonstrated that indices of RV systolic function had shown decrease after closure of ASD. We thought that the observed decline in RV systolic function indices do not reflect a true functional loss, instead it is the result of normalization of cardiac geometry and remodeling after shunt disappearance. There were significant differences in RV geometric and systolic function indices between surgical and percutaneous device closure groups. It is possible to think that RV function remains high normal long before irreversible RV dysfunction occurs, and early intervention before this critical point may unload right ventricle and improves pump efficiently.