الفهرس 
AbstractOnly 14 pages are availabe for public view
 |  | from | 109 |  |  |
| | | from | 109 | | |
Abstract
Type 1 and type 2 diabetes can have severe complications such as diabetic nephropathy. This is considered one of the most common causes of chronic kidney disease. Much research effort is being put into how to diagnose diabetic nephropathy in diabetic patients.
A large number of biomarker studies were published on markers in plasma or urine, either to distinguish patients with or without diabetic nephropathy or to expect the renal outcome in those patients with diabetic nephropathy.
A prospective case-control study was conducted in the present. There were 60 patients with T2DM and 30 healthy controls , diabetic patients in our study were diagnosed according to the 2003 American Diabetes Association diagnostic criteria for diabetes. The consecutive patients were recruited from the outpatient and inpatient clinic of the Internal Medicine Department of Beni-Suef University. We further classified the diabetic patients into 3 groups according to their albumin- to-creatinine ratio (ACR).
Detection of SH3YL1 by ELISA technique was done .
The present study showed that there was a significant association between SH3YL1 and DN in patients.