الفهرس 
Embryology and development of the prostate glandOnly 14 pages are availabe for public view
 |  | from | 224 |  |  |
| | | from | 224 | | |
Abstract
Background; Prostate cancer is the second most common cancer in men worldwide. Two thirds of prostate cancer cases are diagnosed in the more developed regions of the world.
Aim and objectives: The aim of this study was to evaluate the role of MRI imaging in staging of prostate cancer based on Prostate Imaging Reporting and Data System (PI-RADS) version 2.
Subjects and methods: Thirty male patients were included in our study. They were referred to the department of Radiology, Minia Oncology Center with clinical and pathological diagnosis of prostatic carcinoma during the period extended from January 2019 to January 2021.
Results: There was a statistically significant difference between PIRADs 4 and PIRADs 5 lesions as regard patients’ PSA, with higher values among PIRADs 5 cases. There was a statistically highly significant difference between PIRADs 4 and PIRADs 5 lesions as regard patients’ Gleason score, with higher values among PIRADs 5 cases.
Conclusion: MRI examination of the prostate gland has a high specificity and sensitivity in primary diagnosis or staging over clinical assessment alone (PSA level and DRE), and other modalities like ultrasound. mp-MRI is considered the best anatomical and functional imaging modality that is used for detection and characterization of prostate tumors and for clinical staging of patients with prostate cancer, including (T1, T2 and DWI & ADC). The Prostate Image reporting of prostate MRI adheres strictly to PI-RADS™ v2 guidelines which aimed at standardizing the acquisition, interpretation and reporting of prostate MRI. ADC value is used differentiation between benign and malignant lesions, main ADC value of the malignant lesions below 1x10- 3cm/s best applicable for peripheral zone lesions.