Search In this Thesis
   Search In this Thesis  
العنوان
Evaluation of antioxidant, antibacterialand anticancer activity of cymbopogon citratus, artemisiaabsinthium and mentha longifolia leaves /
الناشر
Nessrine Mohamed Mostafa Abdelgwad ,
المؤلف
Nessrine Mohamed Mostafa Abdelgwad
هيئة الاعداد
باحث / Nessrine Mohamed Mostafa Abdelgwad
مشرف / Ebtesam Abdelmoniem Mahmoud
مشرف / Eman Ahmed Hanafy
مشرف / Samia Ali Alaskalany
تاريخ النشر
2021
عدد الصفحات
110 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Biochemistry
تاريخ الإجازة
01/02/2021
مكان الإجازة
جامعة القاهرة - كلية الزراعة - Agricultural Biochemistry
الفهرس
Only 14 pages are availabe for public view

from 156

from 156

Abstract

The study aimed to investigate and compare the antioxidant, antibacterial, and anti-cancer activities of lemongrass (Cymbopogon citratus), wormwood (Artemisia absinthium), and peppermint (Mentha longifolia) for methanol, n-butanol, and ethyl acetate successively extracts and their essential oils for beneficial effects. Different extracts by using HPLC showed that lemongrass, wormwood, and peppermint contain many compounds of polyphenols and their essential oils were identified chemical composition using the GC-MS technique. The MeOH extracts have the highest concentration of antioxidant activities than n-BuOH and EtOAc extracts using DPPH, ABTS, and FRAP methods and the plant’s essential oils were monitored by radical scavenging assay (DPPH). The lemongrass and wormwood EOs contain the highest TPC than peppermint while lemongrass EtOAc, wormwood and peppermint MeOH extracts contain the highest TPC. Furthermore, the antibacterial activites were evaluated for all plants extracts and their essential oils against E.coli, S. typhimirium and S.aureus.where The inhibitory effect of lemongrass, peppermint, and wormwood EOs was higher against Gram-negative bacteria while lemongrass and wormwood MeOH extracts had a higher inhibitory effect against S.typhimirium (26mm and 23.1mm, respectively) but peppermint MeOH extract showed a higher inhibitory effect against S. aureus was 15mm.The possible anti-cancer activity was determined in vitro against colon cancer, breast cancer, and normal human lung cell lines for plants methanol extract and their essential oils