الفهرس 
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Abstract
Background: Acute myocardial infarction is commonly defined pathologically as a cardiomyocyte death due to a prolonged ischaemia resulting from an acute imbalance between oxygen supply and demand. Coronary artery disease is the main cause of mortality worldwide. AMI mainly affects patients older than 40 years of age, however, young can suffer MI. Coronary artery disease is becoming an epidemic in the developing countries, where it occurs in younger persons at greater rates. Young patients tend to have different clinical characteristics and prognosis compared to older patients. Consequences of MI can be devastating particularly at a‘‘young’’age due to its greater potential impact on the patient’s psychology, ability to work and the socioeconomic burden . Acute myocardial infarction is less frequent in young adults than in older individuals as it occurs in only 2% to 6% in the younger population. Primary PCI is the treatment of choice for STEMI if it can be performed in a timely manner ideally within 90-120 minutes of contact with a medical provider. Aim: This study aimed to assess the differences in risk factors and clinical characteristics between young and older AMI patients. Patients and methods: This study was carried out on 60 acute myocardial infarction patients treated with primary PCI at Cardiology Department, Tanta university hospitals and National heart institute. They were divided into: group I: 30 patients less than 40 years old and group II: 30 patients more than 40 years old. Inclusion criteria: We included all consecutive patients diagnosed with Acute myocardial infarction and treated by primary PCI Exclusion criteria: 1- Patient refusal. 2- Malignancy. 3- Liver disease. 4- Renal failure on dialysis. 5- Bleeding disorders. All patients were subjected to the following: 1.Complete history taking: 2- Full clinical examination and cardiac assessment. 3-Electrocradiogram (ECG). 4-Echocardiography 4-Primary percutaneous angioplasty. 5- Laboratory investigations. Results: Concerning age there was statistically significant difference between both groups while there was no statistical significant difference regarding to sex. regarding risk factors there was statistical significant difference between both groups regarding to hypertension, DM, previous MI, cerebrovascular disease and drug abuse. Regarding to labotary investigation, there was no significant statistical difference regarding CK, CKMB, creatinine and random blood sugar. There was no statistical significant difference regarding to culprit artery and TIMI flow after PCI while there was statistical significant difference regarding to number of vessels involved. Regarding to outcome there was no statistical significant difference between both groups regarding to acute HF, cardiogenic shock, re-infarction, and death. As regarding to bleeding, it was statistically significant higher in group II.