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Abstract Study Objective: To explore the relationship among umbilical artery Doppler indices and certain hematological parameters (NLR, MPV, PLR and RDW), and the severity of preeclampsia. Design: A prospective cross sectional study. Methods: Nine hundred and fifty pregnant women were included and divided into severe preeclampsia group (200), non-severe preeclampsia group (250) and control group (500). Umbilical artery Doppler indices as well as the hematological parameters were measured. Neonates were assessed as regards APGAR score at 1 and 5 minutes and neonatal birth weight. Results: Umbilical artery RI and PI showed positive correlation with SBP (r=0.156 and 0.218, P value=0.019 and 0.002, respectively). Each of the UA RI, PI and S/D were significantly negatively correlated with AFI, APGAR 1 minute, APGAR 5 minute and NBW ( RI correlations: r= -0.572, P value {u02C2}0.001: r = - 0.319, P value {u02C2}0.001: r= -0.357, P value {u02C2}0.001; r 0.357, P value {u02C2}0.001; r= - 0.596, P value {u02C2}0.001, respectively; PI correlations: r= -.0397, P value {u02C2}0.001; r= -0.288, P value {u02C2}0.001; r= -0.304, P value {u02C2}0.001; r= -0.426, P value {u02C2}0.001, respectively; SD correlations: r= -0.525, P value {u02C2}0.001; r= -0.405, P value {u02C2}0.001; r= -0.463, P value {u02C2}0.001; r= -0.466, P value {u02C2}0.001, respectively). NLR showed significant negative correlation with APGAR score at 1 minute and NBW (r= -0.162, P value=0.022; r= -0.237, P value = 0.001) |