الفهرس 
Correlation of a new developing index to conventional visual field parameters in glaucoma progression
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Abstract
Purpose: The aim of the study is to measure the Glaucoma Rate Index (GRI) cut off for glaucoma progression and to correlate the GRI with the Mean Deviation (MD), Visual Field Index (VFI), and Guided Progression Analysis (GPA). Methods: This is a longitudinal, observational study. GRI cutoff of 8486 eyes of 4610 primary open angle glaucoma patients with {u2265} 6 VFs and {u2265} 3 years of follow-up was calculated. GRI values of those patients were evaluated for correlation with Mean Deviation (MD) and Visual Field Index (VFI) rates. A subset of 253 primary open angle-glaucoma patients were evaluated for detection of progression with the following methods: Glaucoma Rate Index (GRI), guided progression analysis (GPA), mean deviation (MD), and visual field index (VFI) rates. Results: The results showed an estimated cutoff value for GRI approximately {u2013} 6 for changing and stable VF series. There was a significant good positive correlation between GRI and Mean Deviation Rate (MDR) (r=0.77, p<0,001) & also a significant good positive correlation between GRI and VFI slopes (r =0.695, p < 0.001). GRI had the highest proportion of series detected as progressing (217 patients), followed by GPA (151 patients). MD rate, and VFI rate had the lowest proportion of series detected as progressing (114 & 83 patients). GRI exhibited moderate agreement with MDR (k = 0.460), while exhibiting a fair agreement with GPA & VFI methods Conclusions: GRI had the highest proportion of series detected as progressing. MD rate, and VFI rate exhibited the lowest proportion of series detected as progressing. Of all the methods tested, GRI had the best ability to detect glaucomatous progression in the VF sequences. GRI exhibited moderate agreement with MDR, while exhibiting a fair agreement with other methods