الفهرس 
Title:The impact of psychiatric disorders of parents on the severity of substance use disorder in their offspring
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Abstract
Background There is a lack of evidence in the literature about the impact of offspring addiction and their parents’ mental health. So we aim to explore psychiatric disorders in parents of patients with substance dependence and their effect on the severity of their addiction. Materials and methods This is a cross sectional study contained 150 patients and their parents whom were diagnosed with substance dependence according to DSM-IV criteria. Patients were recruited form Psychiatry and Addiction Prevention Hospital of Cairo University; Faculty of Medicine Results In the patients group, mean age was 24.89 (±4.52) and ranging from 18 to36 years. 96% of them were males 4% were females. In the parent group, mean age was 51.59 (±5.48) and ranging from 49 to 65years. 84% of them were mothers 16 % were females. Patients group was associated with moderate degree of education (46.7%), 73.3% were single and 64% were unemployed. Anxiety disorders (80%) and depressive disorders (69.3%) were the most prevalent among parents group. ASI score was a statistically significant in predicting the incidence of parents psychotic and schizoid disorders (100% sensitivity, 86.3% specificity, AUC=0.887, P value <0.0001).Besides we found a significant correlation between patients ASI scores and parents psychiatric disorder Conclusion This result emphasizes the relation between patient substance use disorder and psychiatric disorder of their parents. Patients ASI score may be a possible measure for parents mental disorder. Further research is needed to validate our findings