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Abstract Background: Central fatigue is a common symptom after stroke{u2019}s incidence. It interferes with the whole rehabilitation process and a limiting factor to actively participate in the environment as well as different functional and daily activities. purpose: To determine the prevalence of central fatigue in stroke patients and to investigate the impact of central fatigue on their functional recovery. methods: One hundred chronic stroke patients from both genders were recruited from The outpatient clinics of The Faculty of Medicine and The Faculty of Physical Therapy, Cairo University. The Study was conducted from 1st July 2019 to 31st December 2019. Demographic data were collected (age, sex). Central Fatigue was assessed by using the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS). The functional recovery was evaluated by the Barthel{u2019}s Index (BI). The demographic data and the functional recovery were correlated to the central fatigues{u2019} outcome measures. results: The prevalence of central fatigue in stroke patients was 62% using the FSS and 66% using the MFIS indicating more sensitivity of the MFIS than FSS. There was a significance increase in the severity and the impact of the central fatigue in the females (p<0.05).The correlation between BI and FSS was a significant moderate negative correlation (r =-0.42, p = 0.0001) and between BI and MFIS was a significant moderate negative correlation (r =-0.50, p = 0.0001). conclusion: The central fatigue is moderately prevalent among chronic stroke patients with 62% using the FSS and 66% using the MFIS showing more sensitivity of the MFIS in evaluating the central fatigue symptoms |