الفهرس 
Title : Study of cardiac involvement in patients with non alcoholic liver disease patients
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Abstract
Background and aim: It is estimated that NAFLD will become the most prevalent cause of chronic liver disease in the near future. The burden of NAFLD though extends beyond the liver and several organ systems are known to be affected. A heightened cardiovascular morbidity is known to be among the leading causes of adverse events in this patients group. The aim of our study was to determine the association of cardiac disease with non alcoholic liver disease and investigate the extent of cardiac disease in relation to severity of NAFLD in an Egyptian population. Methods: This was a cross sectional study on 80 NAFLD patients who underwent transient elastography, CAP measurement, Echo cardiography, carotid Duplex and atherosclerotic cardiovascular disease (ASCVD) 10 year risk assessment, and was compared to 20 controls.Results: left atrial dimensions (3.7±0.5 cm vs 3.3±0.4cm), interventricular septum diameter (0.9±0.2 cm vs0.8±0.1 cm ), left ventricular end diastolic diameter (5.2±0.5 cm vs 4.5±1.3 cm) , left ventricular posterior wall diameter (0.9±0.2 cm vs 0.8±0.1 cm), tissue Doppler imaging lateral S wave (10.2±1.7 mm/s vs 12.3±1.7 mm/s) , tissue Doppler imaging lateral E (14.3±3.4 mm/s vs 21±17.1 mm/s), tissue Doppler imaging E lateral e (5.4±1.6 mm/s vs 4.1±1.1 mm/s ), tissue Doppler imaging medial E wave (10.1±2.1 mm/s vs 11.5±2.4 mm/s ) and right ventricular basal diameter (3.8±0.4 cm vs 3.6±0.5 cm) as well as carotid intimal medial thickness (0.7±0.1 mm vs 0.5±0.1 mm) showed statistically significant differences in NAFLD patients compared to age matched controls (p value > 0.05). Aortic diameter, RV mid. and carotid intimal medial thickness were significantly related to steatosis severity, p values 0.03, 0.017 and >0.001 respectively