الفهرس 
Evaluation of bond strength, setting time, solubility of bio-ceramic sealer before and after mixing with prednisolone powder
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Abstract
Aim: To evaluate the effect of mixing Sure-seal root bio-ceramic sealer with prednisolone on sealer{u2019}s bond strength, setting time and solubility compared to Sure-seal root bio-ceramic sealer without prednisolone in single rooted mandibular premolars. Methods: Setting time test: sixteen Plaster of Paris molds (eight molds for each group) were soaked in distilled water for 24 hours then filled with the non-modified and modified sealer after addition of previously ground prednisolone powder to sealer and obtaining a homogenous mix. Setting time was calculated by using the Gilmore needle till the time that the needle probe fail to make indentation on the sealer{u2019}s surface. Solubility test: Fourteen split Teflon molds (Seven molds for each group) were filled with non-modified and modified sealer as we mentioned before. Molds were placed between two pieces of wet cloth and two-glass slabs then kept in an incubator. Solubility was calculated as a percentage of mass loss at 24 hours, 7, 14, 28 days to determine the effect of time on the material solubility.Bond strength: Twenty straight single-rooted permanent premolars were prepared and divided into two group (ten for each group). Teeth were obturated using non-modified and modified sealer with a matching gutta-percha cone (single cone obturation technique). Two successive middle discs were obtained from each tooth with standardized thickness of 2 mm. Discs were mounted into apico-coronal direction and subjected to the plunger tip of the Universal test machine to determine the push-out bond strength of the sealer to root canal dentine at 24 hours and 28 days and to evaluate impact of the time on the push-out bond strength.Results: The addition of prednisolone powder to Sure-Seal Root BC-Sealer caused a statistically significant increase in the setting time and the solubility of the sealer and a statistically significant decrease in the push-out bond strength to root canal dentin