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Abstract Introduction: Most series of laparoscopic radical nephrectomy (LRN) are confined to T1-tumors. However, there are few publications that address the role of LRN for large renal tumors. With the increasing comfort and experience with minimally invasive techniques, the indications for LRN have expanded to include larger renal tumors. Initially, laparoscopic procedures were reserved for patients at low risk. However, with increasing experience, laparoscopy has been extended to older patients, patients with significant comorbidities, and patients with previous abdominal surgeries. In more recent years, the advent of the robotic approach has prompted the adoption of robot-assisted laparoscopy for radical nephrectomy. Nevertheless, the higher costs of robotic surgery have limited the widespread use of robotic radical nephrectomy because of the equivalent results obtained with the standard laparoscopic approach.Aim of work: In our prospective case series, we present our experience regarding the perioperative morbidity and surgical outcome of laparoscopic radical nephrectomy in the management of renal tumors and the effect of tumor size on the early outcomes. We further attempt to assess the impact of extending the spectrum of laparoscopy to the management of larger, locally advanced tumors (T2 and greater) on the perioperative and early outcomes such as EBL, operative time, intra-operative complication, residual tumor tissue, surgical margin and the rate of conversion to open surgery |