الفهرس 
Title : Future contribution for analytical quality control of some hydroxyl and/or amine containing drugs
ContentsOnly 14 pages are availabe for public view
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Abstract
Quantitative analysis of pharmaceuticals is necessary throughout the various stages of drug development and manufacture. It is considered advantageous to explore accurate rapid methodologies that are low in cost and do not require hazardous solvents, prolonged sample pretreatment or extraction steps. from this perspective, this thesis is concerned with the quantitative determination of pharmaceutical compounds either alone or in their mixtures in the presence of excipients, preservatives and/or potential impurities. These drugs include; losartan potassium, lidocaine hydrochloride, cetylpyridinium chloride, oxeladine citrate, diphenhydramine hydrochloride, guaiphenesin. Various analytical methods were implemented for the simultaneous analysis of these formulations. The applied techniques include spectrophotometry, high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC), ultra high performance liquid chromatography (UPLC) and electrochemistry. Our scientific motivation was to develop simple, accurate, reproducible and rapid analytical methods, which would be feasible and sensitive for the determination of the studied drugs. The proposed methods were validated according to ICH-guidelines. The greenness of the proposed methods was assessed via NEMI, Analytical Eco-Scale, GAPI and AGREE tools