الفهرس 
Management of advanced cases of non-ischemic diabetic foot infection with conventional dressing versus Negative pressure wound therapy
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Abstract
Background: Negative pressure wound therapy (NPWT), also called vacuum-assisted closure, is an adjunctive therapy used in the management of open wounds that applies sub atmospheric pressure to the wound surface. Aim of the Work: To compare the efficacy of negative pressure wound therapy with conventional wound dressings Patients and methods:A Randomized controlled study including 60 patients randomized into two groups 30 patients for (NPWT) &30 patients for conventional dressing, suffering from diabetic foot wounds with infection, necrotic tissue, ulcer.Results: (43.3%) in the NPWT group were females, (56.7%) were males. (36.7%) in the Conventional treatment were females whereas (63.3%) in the Conventional treatment were males. Both groups were classified according to type of the wound, clean or infected, need of surgical debridement. At 3 months follow up,group NPWT 24(85.7%) cured with complete healing, 4(14.3%) patients grafting wasdone, also 2 of 30 patients stopped, one withdrawn his consent and the other had below knee amputation.In conventional dressing group 14(51.9%) only had complete healing and 4(14.3%) grafted,9(33.3%) of 30 patients still on dressing,3 patients lost from analyzation of the study with major complication in the form of major amputation. Conclusion: The rate of granulation tissue formation, wound surface area, overall graft survival was better in NPWT group as compared to conventional dressing group, also the overall hospital stay,amputation rate was less in the NPWT.Thus,NPWT can be considered as a superior option in the management of diabetic foot wounds, holds promising resultsin decreasing the number of amputations in diabetic foot