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Abstract Abstract: Introduction: iron deficiency is a frequent cause of anemia in liver transplant recipients, especially children. Aim of the work: We aimed to assess iron homeostasis in children who have undergone living related liver transplantation (L.R.L.T.). Patients and methods: The study was conducted on 35 children who have undergone LRLT. The patient characteristics, frequency of infection and rejection episodes, Laboratory investigations including complete blood picture (CBC) and Iron profile (TIBC, Serum iron and ferritin during patient follow up were reported. Results: 68.58% of our patients were males) and 31.42% females Their ages ranged from 1.3-15 years at time of liver transplantion with mean of 7.18 ± 3.8 years. The mean duration since liver transplantation was 4.83±4.2 years. The commonest diagnosis was High GGT Cholestasis (34.7%) followed by biliary atresia (21.7 %). 13% of patients had low Hb (5.7% had normocytic normochromic & 11.4% had microcytic hypochromic anemia). the means of iron parameters were within normal ranges. Serum iron showed significant negative correlation with WBCs (P < 0.05). The iron parameters levels were not different in patients with no rejection or only one attack of rejection and the patients with multiple rejection episodes (P > 0.05). Conclusion: anemia is a common problem in pediatric LT. Iron status checkup should be a part of long-term follow up of solidorgan transplant. |