الفهرس 
Title : Application of nanotechnology in antimicrobial therapy for endodonticsOnly 14 pages are availabe for public view
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Abstract
Bacteria play a pivotal role in the initiation and progression of pulpal and periapical pathology. They enter the root canal and invade the dentinal tubules to varying depths of 200 æm{u2013}1500 æm. Bacteria present inside the dentinal tubules hinder the effects of host defense cells and molecules, and systemically administered antibiotics. The success of root canal treatment depends upon effective control of this intracanal infection. Complete elimination of microbes from the root canal system is difficult to achieve, owing to its anatomical complexities and limited access to the instruments and irrigants used. Hence, the use of an intracanal medicament with antimicrobial properties is considered important in order to eliminate the residual bacteria. However, limited permeability of conventional medicaments into the dentinal tubules negates their antimicrobial potential. Also, leakage of the drug from the target site, short residence time and frequent use of the drug is increased, which indicates the side effects of the drug used. As a result, nanoparticles by virtue of their size can be effectively delivered into the complex anatomies of the root canal system. Also, a medicament that penetrates deeper into the dentinal tubules may not only serve as a blocking agent, that also prevent microbial repopulation, but also inactivates them in the tubules