الفهرس 
Stroke SubtypesOnly 14 pages are availabe for public view
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Abstract
Background: Available data collected from patients of different types of cerebrovascular strokes can detect risk factors, severity and clinical outcome of these patients. Differentiating between different types of strokes is mandatory for early diagnosis and proper management. The aim of this study is to compare between cerebral small vessel disease with lacunar infarctions and internal border zone infarctions regarding vasomotor reactivity by using Transcranial color- coded duplex and its correlation with their MRI perfusion, disease severity and outcome. Results: On admission, 56.7% of patients in lacunar stroke had impaired reactivity versus 100% of patients in internal borderzone group. At 3 months follow up, this number dropped to 23.3% in lacunar group, but persisted as 100% in internal borderzone group. On comparing the 3 perfusion parameters between the 2 groups, there was statistically significant impairment in all parameters in patients with internal borderzone infarction than patients with lacunar infarction (longer time to peak, decreased cerebral blood flow and cerebral blood volume). By comparing the severity of the stroke by using National Institute of Health and Stroke Scale, it was found that patients with internal borderzone infarction had higher disability than patients with lacunar infarction on admission and on discharge. At 3 months follow up, the lacunar group had a better outcome than of the borderzone group. Conclusion: Patients having internal borderzone infarction had higher clinical disability and worse prognosis, together with more impairment in vasomotor reactivity and MRI perfusion parameters than patients having lacunar infarction.