الفهرس 
Introduction & RationalOnly 14 pages are availabe for public view
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Abstract
Psychogenic nonepileptic seizures are form of conversion disorder as paraoxysmal episodes resembling epileptic seizures while lacking electroencephalogram correlation.
Creatinine kinase is a muscle specific enzyme which may be useful marker for differentiation of psycogenic non epileptic seizures from generalized tonic colonic seizures. Also, prolactin is apolypeptide secreted by lactotrophic cells, during epileptic seizures; propagation of epileptic discharges may be associated with prolactin release from hypothalamus stimulation.
This prospective cohort study was conducted on 20 patients with GTCS and 20 patients with PNES who were presented in Suez Canal University Hospital to assess the ability of serum levels of creatinine kinase (CK) and prolactin in differentiation between GTCS and PNES.
The current study found statistically significant older age with psychogenic non epileptic seizures compared to GTCS with p-value=0.037, while there was no gender difference between both groups.
Our study found no statistically significant difference between GTCS and PNES as regards serum Na and K levels with p-value >0.05.
As regards EEG in our study, 75% of patients with GTCS had positive EEG findings while only 10% of PNES had positive EEG findings.
Our study found statistically significant higher CK level in GTCS compared to psychogenic non epileptic seizures with p-value <0.001.