الفهرس 
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Abstract
This study is a retrospective observational study that included data of a hundred hospitalized patients diagnosed with COVID-19 infection by a positive RT-PCR assay of a specimen collected via nasopharyngeal swab. The study was conducted in the period between the first of December 2020 to 31 may 2021 in Covid-19 isolation wards and ICU, in Benha Teaching Hospital. Patients hospitalized for less than 48hs, and patients with known end-stage kidney disease (ESKD), on maintenance hemodialysis, and/or renal transplant recipients were excluded from the study. The demographic, clinical, and laboratory data included were collected from medical records, patients’ follow-up, and charts. The results were as follows:
The mean age of the studied cases was 53.29±8.32 with minimum 28 and maximum 71 years and mean BMI was 29.99±4.26, the means of SBP, DBP, HR, RR and SPO2 were 117.8±16.03, 76.40±9.9, 88.59±7.3, 22.28±2.95 and 91.29±6.93 respectively, the majority of cases were males (66%) while females were (34%). Regarding risk factors 30% of the cases were smokers, 46.0% were Diabetics and 30% had hypertension, and regarding comorbidities the frequency of respiratory, cardiac and Immune-suppressive diseases were 16.0%, 24.0% and 14.0% respectively. Regarding CT chest 55% were CORAD I, 26% were CORAD II and CORAD III were 19%, and regarding severity 54.0% were moderate, 24.0% were sever and 22.0% were critical. As regards mortality rate 20.0% of studied cases died and 80.0% survived. Comparison between patients with and without AKI revealed that AKI was significantly associated with older age, high BMI, presence of respiratory diseases, and administrating immune-suppressive drugs were. AKI cases were significantly associated with higher SOFA score, Critical severity and Invasive respiratory support. D dimer, CK and Cr were significantly higher among cases with AKI but GFR was significantly lower. AKI cases significantly associated with higher mortality. Multivariate logistic regression for predictors of AKI revealed that Severity of infection, SOFA score, Creatinine, GFR and D-dimer were significant independent predictors for AKI.