الفهرس 
CAESAREAN SECTIONOnly 14 pages are availabe for public view
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Abstract
Background: Cesarean section is one of the most common operations worldwide. Uterotonic agents are used to decrease intraoperative and postpartum blood loss, most commonly Oxytocin. Many routes and regimens are used for administering Oxytocin intraoperative. We aim to optimize the timing of administering IV Oxytocin to decrease intraoperative and postpartum blood loss.
Objective: To evaluate superiority of early IV Oxytocin administration before uterine incision compared to IV Oxytocin administration after cord clamping in elective cesarean section regarding intraoperative and postoperative blood loss.
Patients and Methods: This single blinded randomized controlled clinical trial was performed on total 160 third-trimesteric pregnant women (< 37 weeks) who admitted for elective caesarian section and willing to participate in the study at tertiary care hospital at Ain Shams Maternity University hospital starting from June 2021 till March 2022.
Results: The current study results revealed that additional uterine stitches to maintain hemostasis were significantly less frequent among Before uterine incision group (p value=0.005) with no statistically significant differences as regards uterine artery ligation and blood transfusion among the studied groups. The current study results revealed that the need for additional uterotonics postoperatively was significantly less frequent among Before uterine incision group (p value= 0.032).
Conclusion: As evident from the current study, intravenous oxytocin administration can be safely used as routine uterotonic during elective CS to reduce blood loss. It also showed that early administration of intravenous oxytocin before the uterine incision is superior to oxytocin administration after cord clamping in reducing blood loss and the need for additional uterotonics and surgeries during elective CS.