الفهرس 
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Abstract
Preeclampsia (PE) is one of pregnancy related hypertensive disorders, affecting 2-8% of pregnant females and is an important etiology of perinatal mortality and maternal morbidity. In addition, PE is commonly associated with intrauterine growth restriction (IUGR), iatrogenic preterm delivery and placental abruption, which are additional main causes of adverse outcome Placental dysfunction plays a crucial role in the pathogenesis of related pregnancy complications. Therefore, placental volume, weight, surface area, and insufficiency, and vascular indices are significant when investigating early fetal growth restriction and gestational complications The aim of the study was to determine the sensitivity of placental volume at11th week to 13th week+6 days in predicting preeclampsia. To elucidate this aim 250 pregnant women at11th week to 13th week and follow up till 34th week were included in the current study. The mean age of the studied cases was 26.97±5.6 years, and the mean BMI was 30.75±2.25 . Also, the mean Hb was11.32±0.86, and the mean white blood cells was 8.68±2.5 and the mean gestational age was 12.7 ± 0.35. Also, 70% of the participants were housewives, and having 2 children. As regard to blood pressure, systolic blood pressure was 108.2±10.1 and diastolic blood pressure was 71.9±7.58. Furthermore, the mean placental volume in all the cases was 53.4 ± 8.5, in the preeclampsia group was43.4 ± 6.4 and in the non-preeclampsia group was 50.6 ± 9.4. There was high significant difference in between two groups regarding to placental volume. There was non-significant correlation in between Placental volume (cm3) and clinical characteristics, age, and obstetric history among preeclampsia cases.. The sensitivity and specificity of placental volume in differentiating between preeclampsia from non-preeclampsia were 60.0%; 60.0% respectively, with a cutoff point of ≥44.25.