الفهرس 
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Abstract
Summary
The present study was conducted at ICU Department, Egypt Air Hospitals in the period from 1/6/2020 to 1/6/2021.
The study included a total of 100 patients with diagnosed Covid 19, (clinically, laboratory and radiologically).
100 patients were admitted to ICU Department, Egypt Air Hospitals.
The result of this study showed that:
1- Description of sex in studied patients, 52% were males and 48% were females.
2- the description of differentiating moderate to severe illness in all patients in studied patients, shows moderate cases 17/100 of males and 19/100 were females while sever cases were 35/100 of males and 29/100 were females.
3-Changes in leucocyte count before and after tociluzumab:
*Before tociluzumab was zero case was less than 4 and 100 cases from (4-11) and zero case more than 11 X 10^3/ul.
*After tociluzumab was 5 cases less than 4 and 10 cases from (4---11) and 85 cases more than 11 X 10^3/ul.
5- Changes in neutrophil count before and after tociluzumab, in which , Before tociluzumab was zero case less than 2000/cmm,70 cases were range from (2000_7000) /cmm and 30 cases were more than 7000/cmm and After tociluzumab was was 2 cases less than 2000/cmm,9 cases were range from (2000_7000) /cmm and 88 cases were more than 7000/cmm .
6- Changes in ferritin before and after tociluzumab, in which , Before tociluzumab was 2 cases less than 200 ng/ml,40 cases were range from (200 ng/ml _1000 ng/ml) and 58 cases were more than 1000 /ng/ml and after tociluzumab was was zero case less than 200 ng/ml, 28 cases were range from (200 ng/ml _1000 ng/ml) and 72 cases were more than 1000 /ng/ml .
7- Changes in procalcitonin before and after tociluzumab, in which , Before tociluzumab was 99 cases less than( 0.1_0.5 ) ng/ml and one case was range from more than0.5 ng/ml and after tociluzumab was was was 44 cases less than( 0.1_0.5 ) ng/ml and 56 cases was range from more than 0.5 ng/ml.
8- show Changes in Interleukin 6 before and after tociluzumab, in which , Before tociluzumab was zero case less than (6)Pg/ml,zero case were range from (6_12) Pg/ml and 100 cases were more than 12 Pg/ml and after tociluzumab was was zero case less than (6)Pg/ml,zero case were range from (6_12) Pg/ml and 100 cases were more than 12 Pg/ml.
9- Overall mortality in studied patients was 74 patients , 37 male and 37 female from the total 100 patients.
10- Types of Organisms differentiation (cultured organisms) in studied patients, which 57% were candida, 21% were MRSA, 15% were Kliebsiella , 10% , Acinobacter and others were 4%.
11- Incidence of improvement to hospital discharge studied patients: from the total 100 patient 26 patients improved to home discharge differentiated moderate to severe