الفهرس | Only 14 pages are availabe for public view |
Abstract Ultrasound usage among pulmonologists has become an integral assessment tool widely used for assessing pleural effusion as well as lung consolidation and peripherally located solid lesions arising from pleura, chest wall and mediastinum. The importance of US-guided procedures grew even over CT-guided procedures due to the wide availability, lightweight, affordability and bedside manner of the procedures as well as being safer, faster than and possibly as accurate as CT guidance. Ultrasound-guided procedures include fine needle aspiration biopsy (FNAB) and core needle biopsy (CNB), both serves as excellent techniques being minimally invasive, compared to the surgical biopsy, and provide enough tissue sample for diagnosis and later supplementary tests needed for tumor workup. Primary objective is to assess the diagnostic yield of ultrasound guided FNAB versus CNB in cases of peripheral lung and pleural lesions and secondary objective is to compare the procedure time, complications, pain score, technical complexity and ancillary molecular tests between FNAB and CNB. CNB duration was longer in patients with peripheral lung lesion when compared to FNAB and the difference observed was statistically significant. (p value <0.0001) CNB duration was longer in patients with parietal pleural thickening when compared to FNAB and the difference observed was statistically significant (p value <0.0230) No statistically significant difference in the incidence of complications between FNAB and CNB in neither in the parietal pleura biopsies nor the peripheral lung mass biopsies. (p = 1.000 and 0.500, respectively). The overall yield of the combined procedures; FNAB and CNB was 96.6% diagnostic; diagnosing 29 patients out of all 30 studied patients. The difference in the overall diagnostic performance between CNB and FNAB showed superior performance of CNB with a statistically significant difference (p value <0.001). The difference in the diagnostic yield between the FNAB and CNB in the benign group was statistically significant (p value |