Search In this Thesis
   Search In this Thesis  
العنوان
Retrospective study of infectious complications of pediatric patients with acute lymphoblastic leukemia during maintenance therapy /
الناشر
Walaa Ahmed Alkady ,
المؤلف
Walaa Ahmed Alkady
هيئة الاعداد
باحث / Walaa Ahmed Alkady
مشرف / Emad Nabil Ebeid
مشرف / Hadeer Ahmad Elmahalawy
مشرف / Youssef Madney Saeed
تاريخ النشر
2018
عدد الصفحات
146 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأورام
تاريخ الإجازة
2/3/2018
مكان الإجازة
جامعة القاهرة - معهد الأورام القومى - Pediatric Oncology
الفهرس
Only 14 pages are availabe for public view

from 166

from 166

Abstract

Background: Infectious complications are a serious cause of morbidity and mortality in cancer patients especially those with hematological malignancies. Decrease the risk of serious and long lasting infections need detailed information about the frequency and characteristic features of infections. Objective: To assess epidemiology of infectious episodes and to evaluate infection related mortality during maintenance phase of chemotherapy. Patients and methods: Retrospective cohort study of infectious complications for ALL pediatric patients who treated at NCI during the period from June 2011 to December 2014. Results: A total of 1052 infectious episodes recorded in 146/152 ALL pediatric patients during maintenance chemotherapy with an average of 7 episodes/ patient and a range of 0-26 episodes/patient. FUO was the most common infectious episodes (36.8%) followed by clinically documented infections (26%), viral (17%), bacterial (16.8%) and fungal infections (3.6%). Most of infectious episodes 412/1052 (39.16%) occurred during early phase of maintenance chemotherapy w (1-19). Standard and high risk group reported 609/1052 (58%) infectious episode of which (44%) reported during early phase, in comparison to low risk group reported 433/1052 (41.2%) infectious episode, of which (33%) episodes reported during the early phase