الفهرس 
In vitro activity of single and combined antibiotics against carbapenem resistant enterobacteriaceae clinical isolates in relation to their resistance genes
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Abstract
The prevalence of carbapenem-resistant Enterobacteriaceae (CRE) is on the rise worldwide, posing a major public health threat as well as a serious concern for infection control management. Programs and policies for the rational use of antibiotics are urgently needed to minimize more colonization with CRE with restriction of extended spectrum carbapenems use. The aim of our study was the in vitro evaluation of the effectiveness of different single and combined therapeutic options against CRE infections. The isolates were collected at Theodor Bilharz Research Institute. CRE were detected using disc diffusion test as a screening test and carbapenemase enzyme production was confirmed by Carba NP test. Hospital acquired infections were frequently high representing 80% of the CRE isolates