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العنوان
Investigation of the chemical composition and antimicrobial activity relationship of essential oils from certain myrtaceous plants using spectroscopic techniques coupled to chemometrics /
الناشر
Nermeen Farag Habib Farag ,
المؤلف
Nermeen Farag Habib Farag
هيئة الاعداد
باحث / Nermeen Farag Habib Farag
مشرف / El-Sayeda Ahmed El-Kashoury
مشرف / Shadia Mazloum Azzam
مشرف / Enas Hussien Abdelrahman
مناقش / Sherweit Hamed El-Ahmady
تاريخ النشر
2018
عدد الصفحات
232 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
العلوم الصيدلية
تاريخ الإجازة
24/6/2018
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Philosophy in Pharmaceutical
الفهرس
Only 14 pages are availabe for public view

from 290

from 290

Abstract

Investigation of the essential oils from selected species of five Myrtaceae genera (Eucalyptus, Corymbia, Syzygium, Eugenia and Melaleuca) and quality assessment of their available commercial products in the local market were performed. This was achieved by using GC-MS and GC-FID analyses for identification and quantification of the chemical composition. Spectroscopic analysis of different oil samples was also carried out using ATR-IR spectroscopy to provide information about their chemical classes. In addition, the labeling and packing quality of commercial products was assessed by applying FDA and ISO specifications. They were also assessed for conformity with the British Pharmacopoeia (BP) standards regarding their organoleptic properties (color and odor) and physical characters (optical rotation and refractive index). PCA and HCA of GC-MS and ATR-IR data resulted in the rapid classification of the essential oil samples and their major components. Clustering analysis based on ATR-IR spectra of the investigated essential oils showed a clear segregation related to the molecular differences among individual plants and comparable to the GC-based classification. ATR-IR and GC (based on peak area) could successfully unveil the adulterated oil samples complexity