الفهرس 
Title: Retrospective study of outcome of primary extra-nodal non hodgkin’s lymphoma. single institute experience at the National Cancer Institute - Cairo University
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Abstract
Background: the study of extranodal lymphomas as a group regarding etiopathogenesis, biologic features, clinical characteristics and outcome has been the subject of various publications. aim of the study: the aim of our research was to study the pattern of primary extranodal lymphoma at nci during the period from january 2008 to december 2012. in respect to; epidemiologic characteristics, presentation, histopathologic charecteristics and treatment outcomes. results: our study included 149 patients with primary extranodal non hodgkin lymphoma.the age of participants ranged from 19 to 77 years with median age 51 years. male to female ratio was approximately 1:1. most patients were presented with stage (i-ii) 106 (85%), while 15% had advanced disease (stage iii and iv). most participants had b cells nhl patients with diffuse large b-cell lymphoma as the most common histologic subtype. gastrointestinal tract was the most common site for primary extranodal lymphoma (32.8%), followed by spleen, head and neck, breast and bone. most of the patients were treated with chemotherapy, the most common used chemotherapy protocol was (chop), with complete response rate (78%). 5 year survival of the whole study population was (64.7%) which is a good prognosis compared to primary nodal lymphoma. disease free survival of the whole study population was (66.7%) and was significantly affected by stage and IPI