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العنوان
Possible role of amiodarone versus propranolol in treatment of chronic theophylline toxicity in rats /
الناشر
Lamiaa Mohammed Meghawery Matter ,
المؤلف
Lamiaa Mohammed Meghawery Matter
هيئة الاعداد
باحث / Lamiaa Mohammed Meghawery Matter
مشرف / ElSayed Mahmoud ElRokh
مشرف / Hisham Attia AlShekhepy
مشرف / Ghada Farouk Saleh
تاريخ النشر
2019
عدد الصفحات
155 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب (متفرقات)
تاريخ الإجازة
22/8/2019
مكان الإجازة
جامعة القاهرة - كلية الطب - Pharmacology
الفهرس
Only 14 pages are availabe for public view

from 173

from 173

Abstract

Background and aim : Theophylline toxicity continues to be a major clinical problem with potentially fatal cardiac and neurological complications .Therefore, the development of agents that have different mechanisms of action and can be used in combination with currently approved medications for the treatment of theophylline poisoning is highly desirable. Objectives: This experimental study was designed to investigate the potential role of amiodarone, the well-known antiarrythmic drug in treatment of chronic theophylline poisoning. Propranolol (non selective B-blocker) is used as a standard drug for comparison. The study was extended to show the potential anticonvulsant and theraputic effect of amiodarone against gastric erosions which occurs with theophylline poisoning