الفهرس 
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Abstract
The aim of this study was to assess prognostic value of PCT and IL-6 for severe disease and outcome in COVID-19.
The present study was carried out at the Clinical Pathology Department, Chest department, Faculty of Medicine, Minia University, through the period from May 2021 to March 2022. It was conducted on 90 individuals after ethical committee approval and a written consent was obtained from relatives of each patient.
The results of this study were summarized as follow:
In terms of age and gender, there was no statistically significant difference.
Both groups investigated had similar levels of diabetes mellitus (DM), high blood pressure (hypertension), and smoking.
Patients with more severe illness had lower haemoglobin (Hb), absolute lymphocytic count (ALC), and platelet count than those with less serious disease.
Diseased groups had greater TLC and absolute neutrophil counts than the control group, and the more serious patients had higher counts.
There was a substantial difference in length of stay in the ICU between the severe and critical groups.
A higher INR and higher random blood glucose levels were seen in patients with a more severe illness than those with a more mild illness.
In the sick group, ALT and AST levels were greater than in the control group, although there was no significant difference between the diseased groups and each other in serum albumin levels.
Each of the sick groups had considerably higher urea and creatinine levels than the control group, and these levels were greater within the diseased groups itself and correlated directly with severity.
All sick groups had considerably higher CRP and D-dimer levels compared to the control group, and the critical group had the highest levels compared to the moderate group.
All the sick groups had PCT and IL-6 and Serum ferritin levels that were considerably greater than those in healthy controls
IL-6 showed strong positive correlation with ferritin, D-dimer, and CRP (r=0.722, 0.801, 0.792) respectively , and moderate negative correlation with absolute lymphocytic count (r= - 0.517) with a significant p value (p=0.0001) for all .
Procalcitonin (PCT) showed strong positive correlation with ferritin, D-dimer, and CRP (r=0.703, 0.721, 0.711) respectively and moderate negative correlation with absolute lymphocytic count with a significant p value (p=0.0001) for all .