الفهرس 
MigraineOnly 14 pages are availabe for public view
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Abstract
Background: migraine is a common complaint in the pediatric population. Estimates of migraine prevalence in childhood and adolescence range from 3% to 10%. Migraine has two major types: migraine without aura and migraine with aura. Recently, association of migraine with metabolic syndrome and insulin resistance has been reported. Metabolic syndrome, a cluster of interacting cardiovascular risk factors including hypertension, insulin resistance, dyslipidemia and central adiposity, is known as a major public health problem due to its association with an increased risk of atherosclerotic cardiovascular disease and type 2 diabetes. Insulin resistance is generally considered to be a root causative factor for metabolic syndrome.
Objective: to correlate between migraine and metabolic syndrome, including insulin resistance.
Patients and Methods: this study is a case control study that was conducted on children aged between 4 and 16 years who were recruited from the pediatric neurology department. The diagnosis of migraine was according to the criteria of the International Classification of Headache Disorders (ICHD) -II criteria. Anthropometric measurements of all subjects were measured. Insulin resistance was assessed by Homeostatic Model Assessment for Insulin Resistance (HOMA-IR).
Results: females were (40%) and males were (60%) among our patients group. Headache with aura was present in 13 (43.3%), Family history was present in 24 (80%), bilateral headache was the most common among our patients (71.4%). There was significant increase in BMI among migraine group with (P-value 0.030). Insulin resistance by HOMA-IR and by QUICKI showed significant difference between migraine and control groups with (P-value 0.007 and 0.033) respectively.
Conclusion: based on our results, it can be concluded that migraine is associated with insulin resistance in 36.7% of patients